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Naringin and other flavonoids have a suppressive activity on the RAAS, as they have been known to inhibit ACE activity, which is vital in the regulation of arterial BP, as it reduces the formation of Ang-II, which is responsible for inducing vasoconstriction and thereby reducing BP [167, 168]

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Inhibition of mitochondrial complex I leading to NAD(+)/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: evidence from an integrative analysis of platelet bioenergetics and metabolomics